OpenSlice is a novel web-based API for large scale data sharing in Mass Spectrometry fully eliminating the need to download RAW datafiles. More documentation will be made available soon, however for the time being, a slightly outdated ASMS2013 talk is available, as well as 4 example D.I.C.E (Distribute Ion Chromatogram Extractor) viewers for the CPTAC Colon Dataset: Ascending Colon: full interactive access to 190 Rawfiles from 12 patients having a tumor in the ascending colon. Data are colored by history of polyps. Lymphatic Invasion: full interactive access to 660 Rawfiles from 44 patients with lymphatic invasion. Data are colored by disease stage. Duplicate: Technical replicates of a patient dataset consisting of 30 Rawfiles (duplicates of 15 fractions). Data are colored by replicate date. Complete: full interactive access to 1402 Rawfiles from 90 patients with Colon cancer. Data are colored by Gender. Note: This will break your browser!!! Currently, only Chrome is recommended for the interactive, browser-based slicing and dicing of these datasets.